How to Disable Chrome Cache – Google Chrome Web Browser. There are often several reasons a person might want to prevent their Chrome Web Browser from Caching pages visited on the internet. One might assume "Disabling Cache" to be an easy option to find and set in Chrome. But currently the only setting to disable cache in Chrome is embedded deep within Developer Tools. In addition, simply disabling cache from within Developer Tools only works as long as the Developer Tools window remains open. As a result that probably isn't going to be a solid solution for the majority of Chrome users.